An international research team led by the University of Leicester has made a breakthrough advance that could pave a new route for the development of anti-cancer drugs.
Biochemistry
Nov 7, 2016
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17
(Phys.org) —There's hope for patients with myotonic dystrophy. A new small molecule developed by researchers at the University of Illinois has been shown to break up the protein-RNA clusters that cause the disease in living ...
Biochemistry
Apr 30, 2013
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It arises from what scientists previously described as "junk DNA" or "the dark matter of the genome," but this gene is definitely not junk.
Cell & Microbiology
Nov 7, 2014
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Researchers from Princeton University and the National Institute of Environmental Health Sciences have discovered how a fruit fly protein binds and regulates two different types of RNA target sequence. The study, which will ...
Cell & Microbiology
Apr 4, 2017
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222
(PhysOrg.com) -- Assistant Professor of Bioengineering Christina Smolke has engineered biological molecules that regulate a cell's behavior by adjusting their own forms and functions in response to the internal conditions ...
Biotechnology
Nov 30, 2010
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1
Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing - a critical step in the earliest stage of protein production. Their study appears in the ...
Cell & Microbiology
Sep 23, 2010
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0
Numerous biological processes depend on molecules called lariat RNAs (LaRNAs). These lasso-shaped structures form in the cell during RNA splicing. During this process, transcribed RNA strands convert to messenger RNA before ...
Biochemistry
May 24, 2012
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RNA is the central tenet of molecular biology, the stepping-stone between DNA and proteins.
Biotechnology
Feb 4, 2021
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572
A research team led by Prof. Xue Yuanchao from the Institute of Biophysics of the Chinese Academy of Sciences has developed a new method for global profiling of in-situ RNA–RNA contacts associated with a specific RNA-binding ...
Cell & Microbiology
Mar 23, 2023
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82
RNA splicing is a major underlying factor that links mutations to complex traits and diseases, according to an exhaustive analysis of gene expression in whole genome and cell line data. Reporting in Science on April 29, 2016 ...
Cell & Microbiology
Apr 28, 2016
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