Scientists at the Technical University of Munich and the Helmholtz Zentrum Muenchen and along with their colleagues from the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Centre for Genomic Regulation ...
Cell & Microbiology
Jul 14, 2011
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There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process. The rule-flaunting ...
Biotechnology
May 17, 2012
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A rare, small RNA turns a gene-splicing machine into a switch that controls the expression of hundreds of human genes. Howard Hughes Medical Institute Investigator and professor of Biochemistry Gideon Dreyfuss, PhD, and his ...
Cell & Microbiology
Aug 21, 2013
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Scientists at A*STAR's Genome Institute of Singapore (GIS), in collaboration with their counterparts from Canada, Hong Kong and US, have discovered a protein mediator SON plays a critical role in the health and proper functioning ...
Cell & Microbiology
Sep 9, 2013
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A research team at Children's Hospital of Philadelphia (CHOP) has developed an innovative computational tool offering researchers an efficient method for detecting the different ways RNA is pieced together (spliced) when ...
Molecular & Computational biology
Mar 25, 2019
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From neurosurgery to bar code readers, lasers have been used in a myriad of applications since they were first introduced in the late 1950's. Now, with the work being done in Jeff Gelles' Lab at Brandeis University, researchers ...
Cell & Microbiology
Mar 10, 2011
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Understanding how RNA binding proteins control the genetic splicing code is fundamental to human biology and disease – much like editing film can change a movie scene. Abnormal variations in splicing are often implicated ...
Biotechnology
Feb 16, 2012
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(Phys.org)—Scientists on the Florida campus of The Scripps Research Institute have designed a compound that shows promise as a potential therapy for one of the diseases closely linked to fragile X syndrome, a genetic condition ...
Biochemistry
Sep 4, 2012
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With over 75 million baby boomers in the U.S. alone, age-related diseases are a major concern in the health care system. The connection between aging and cancer has become a pillar in medicine: we know that as we age, our ...
Biotechnology
Oct 7, 2016
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Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. A new bioengineered reporter system developed at ...
Cell & Microbiology
Jun 4, 2021
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