Probing RNA function with 10,000 mutants
Creating and examining 10,296 mutants of a ribozyme leads to a better understanding of these widespread but understudied RNA molecules.
Creating and examining 10,296 mutants of a ribozyme leads to a better understanding of these widespread but understudied RNA molecules.
Cell & Microbiology
Aug 10, 2016
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Over a century of research has shined light on the once-murky innards of our cells, from the genes that serve as our "blueprints" to the proteins and other molecules that are our cellular taskmasters.
Biochemistry
Jul 21, 2016
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599
Research investigators in Singapore have developed a new high throughput method that identifies how ribonucleic acid (RNA) molecules come together in an unbiased and large-scale manner inside cells. Named SPLASH, or Sequencing ...
Cell & Microbiology
Jul 11, 2016
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Cells contain thousands of messenger RNA molecules, which carry copies of DNA's genetic instructions to the rest of the cell. MIT engineers have now developed a way to visualize these molecules in higher resolution than previously ...
Biotechnology
Jul 4, 2016
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606
For a long time dismissed as "junk DNA", we now know that also the regions between the genes fulfil vital functions. Mutations in those DNA regions can severely impair development in humans and may lead to serious diseases ...
Biotechnology
Jun 2, 2016
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New molecular dynamics research into how RNA folds into hairpin-shaped structures called tetraloops could provide important insights into new treatments for retroviral diseases.
Cell & Microbiology
May 31, 2016
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A key biochemical enables bacteria to repair otherwise fatal damage to their DNA, including that caused by antibiotics. That is the finding of a study led by researchers at NYU Langone Medical Center and published May 20 ...
Cell & Microbiology
May 19, 2016
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(Phys.org)—A team of chemists at Ludwig Maximilian University of Munich has shown how the purines adenine and guanine can be synthesized easily and in reasonable yields, offering more evidence that RNA could have served ...
Research investigators in Singapore have developed a new high throughput method that identifies how ribonucleic acid (RNA) molecules come together in an unbiased and large-scale manner inside cells. Named SPLASH, or Sequencing ...
Cell & Microbiology
May 13, 2016
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23
For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial ...
Cell & Microbiology
May 6, 2016
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