Designing synthetic proteins that can act as drugs for cancer or other diseases can be a tedious process: It generally involves creating a library of millions of proteins, then screening the library to find proteins that ...
Biochemistry
Oct 16, 2018
0
81
FAT10 is a small protein with a huge effect. Its attachment to a target protein is a signal for its degradation. FAT10 is a marking system for degradation that seems to be inefficient. In contrast to its biological competitor, ...
Cell & Microbiology
Sep 4, 2018
0
4
Scientists have found a new method for analysing how active agents affect a specific protein essential for cell survival. Their research could help to quickly develop drugs with fewer side effects.
Biochemistry
Aug 28, 2018
0
5
A joint research team from Russia and the U.K. has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs, or "plastic antibodies." NanoMIPs are synthetic polymers that can function ...
Bio & Medicine
Aug 23, 2018
0
24
The search for new medicinal molecules with predetermined properties is a complex, expensive and time-consuming process, especially in oncology. Modern science allows us to accelerate this search through the use of computer ...
Biochemistry
Aug 14, 2018
0
5
There's a hitch in the swing of a protein that delivers the flu virus. Rice University and Baylor College of Medicine researchers believe this mechanism may be a useful target to stop the virus from infecting cells.
Biochemistry
Jul 24, 2018
0
105
Bacterial systems are some of the simplest and most effective platforms for the expression of recombinant proteins. They are more cost-effective compared to other methods, and are therefore of great interest not only for ...
Biochemistry
Jul 13, 2018
0
6
HITS researchers developed tauRAMD, a tool to predict drug-target residence times from short simulations. The method is illustrated on the cover page of July 2018 issue of the Journal of Chemical Theory and Computation, software ...
Biochemistry
Jul 12, 2018
0
10
For the first time, scientists have directly visualized in real-time structural changes in the surface protein of the influenza virus that may help the virus to fuse with and enter target cells before hijacking their functions. ...
Cell & Microbiology
Jun 28, 2018
0
17
Almost every cell in the human body, from beating heart cells to bacteria-gobbling immune cells, is powered by chemical energy produced by specialized organelles called mitochondria. The process of energy generation creates ...
Cell & Microbiology
May 3, 2018
0
17
