Related topics: genes · protein · amino acids · messenger rna

Why synonymous mutations are not always silent

New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...

Slimming and greening the Chinese food system

On August 29, 2022, a research team led by Prof. Wang Xiaoxi from the China Academy for Rural Development and School of Public Affairs of Zhejiang University, and Prof. Yuan Changzheng from the School of Public Health of ...

Key regulator of cell growth deciphered

The mTOR protein plays a central role in cell growth, proliferation and survival. Its activity varies according to the availability of nutrients and some growth factors, including hormones. This protein is implicated in several ...

A 'door' into the mitochondrial membrane

Mitochondria—the organelles responsible for energy production in human cells—were once free-living organisms that found their way into early eukaryotic cells over a billion years ago. Since then, they have merged seamlessly ...

'Non-essential' building block proves vital to a healthy protein diet

A "non-essential" amino acid—so-called because the body can make it from other nutrients—can act as a nutritional cue to guide the body's responses to a low-protein diet, a RIKEN-led team has found in a study on fruit ...

First mouse model with mitochondrial tRNALeu mutation developed

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...

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