A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.
Analytical Chemistry
Jun 7, 2024
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0
Important nutrients for the first living organisms on Earth may have come from space, according to new research from the University of Hawaiʻi at Mānoa.
Astrobiology
May 30, 2024
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177
New mathematical tools revealing how quickly cell proteins break down are poised to uncover deeper insights into how we age, according to a recently published paper co-authored by a Mississippi State researcher and his colleagues ...
Mathematics
May 21, 2024
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23
A team of researchers has recently demonstrated the utility of employing a previously established screening system to probe the interactions between small molecules and RNA. Their study is published in Communications Chemistry.
Biochemistry
May 21, 2024
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6
By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein.
Biochemistry
May 20, 2024
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46
An increasing number of bacteria have become resistant to many commonly used antibiotics. Researchers from Bochum have discovered a fresh opportunity for a potential active molecule whose predecessor was rejected. By studying ...
Biochemistry
May 16, 2024
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1
In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes ...
Biochemistry
May 3, 2024
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30
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers ...
Biochemistry
Apr 25, 2024
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54
A new computer process developed by chemists at ETH Zurich makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process, detailed in Nature ...
Biochemistry
Apr 24, 2024
1
37
Despite huge advances in our understanding of COVID-19 over the past four years, the disease is still very much among us—and there remains a lot to learn.
Cell & Microbiology
Apr 24, 2024
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28
