Atomic picture of dengue replication could transform antiviral approaches
A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
Cell & Microbiology
Oct 31, 2023
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1
Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs. Details on the findings, which were reported in the ...
Molecular & Computational biology
Sep 7, 2023
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81
Membrane proteins play a pivotal role in various cellular functions and are key targets for pharmaceutical interventions. In fact, approximately 60% of drugs currently available on the market target these specific proteins. ...
Molecular & Computational biology
Sep 7, 2023
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1
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With ...
Molecular & Computational biology
Aug 1, 2023
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235
Ion channels play a crucial role in many cellular processes, including neuronal communication, muscle contraction or cell proliferation.
Cell & Microbiology
Aug 1, 2023
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1
Discovering and developing drugs can be slow, costly and high-risk, but harnessing advances in artificial intelligence (AI) can help with these processes, say Brock University researchers.
Molecular & Computational biology
Aug 1, 2023
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30
Scientists from the Giulio Superti-Furga Lab at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, have developed a new method that allows the discovery of specific inhibitors of a lactate ...
Cell & Microbiology
Jul 28, 2023
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5
Chemists at King's College London have made a breakthrough in the way they develop artificial helix shapes for the amino acids that constitute proteins. These new synthetic shapes have the potential to transform processes ...
Analytical Chemistry
Jul 19, 2023
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14
Griffith University researchers have played a key role in using DNA "origami" templates to control the way viruses are assembled.
Bio & Medicine
Jul 17, 2023
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54
A team of investigators in the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a novel protein region responsible for regulating ...
Cell & Microbiology
Jul 14, 2023
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25