Related topics: stem cells · embryonic stem cells · cells · skin cells · genes

A key function for tight junctions in embryo models

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these signaling molecules guide ...

Uncovering hidden mitochondrial mutations in single cells

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies ...

Simple but revolutionary modular organoids created with hydrogels

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without ...

Researchers generate patient-specific cells from thymus organoids

Researchers have used pluripotent stem cells to make thymus organoids that support the development of patient-specific T-cells, researchers report March 23 in the journal Stem Cell Reports. The proof-of-concept work provides ...

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