Ultrasuperovulation is an advanced technique that significantly increases the number of oocytes produced by female mice. However, existing ultrasuperovulation techniques have a low fertilization rate, probably caused by the ...
Plants & Animals
Mar 13, 2023
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36
Reproduction is highly dependent on diet and the ability to use nutrients to grow and generate energy. This is clearly seen in women, who must provide all the nutritional building blocks required to support a growing embryo. ...
Cell & Microbiology
Jan 28, 2016
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20
How do you study reproductive aging, the biological clock that affects fertility, in the lab? Researchers at Howard Hughes Medical Institute's Janelia Research Campus use a surprising animal: the roundworm C. elegans.
Cell & Microbiology
Sep 14, 2023
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4
In mammals, females have a limited supply of oocytes. Oocytes have a unique epigenome with approximately half the DNA methylation of sperm, and the most terminally differentiated somatic cells. Until recently, regulators ...
Biotechnology
Nov 29, 2018
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55
Genetic studies in mice have identified a molecular mechanism crucial to maintaining egg cells in a dormant state to ensure female fertility. This work by A*STAR identifies a potential method to prevent infertility when the ...
Cell & Microbiology
Apr 5, 2017
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4
The promise of generating truly pluripotent stem cells from terminally differentiated adult cell types continues to captivate scientists who envision great potential for therapeutic interventions. The two primary methods ...
Cell & Microbiology
Jul 3, 2018
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4
Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without incurring damage. In mice, ...
Cell & Microbiology
Feb 20, 2024
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70
Safe and high-quality fertility preservation is of growing significance for women in clinical trials. Current primary methods for cryopreserving human oocytes are slow freezing and vitrification, but existing techniques pose ...
Bio & Medicine
May 15, 2024
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1
A protein helps direct the flow of materials in the Drosophila ovary during the development of egg cells, according to a Northwestern Medicine study published in Current Biology.
Cell & Microbiology
Jun 15, 2021
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14
Northwestern Medicine scientists have identified how cytoskeletal proteins contribute to the growth of developing eggs in fruit flies, findings that further the field's understanding of how egg cells form and differentiate ...
Cell & Microbiology
Oct 10, 2023
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