Oocytes: Going with the flow

Most cells rely on structural tethers to position chromosomes in preparation for cell division. Not so oocytes. Instead, a powerful intracellular stream pushes chromosomes far-off the center in preparation for the highly ...

Fishing games gone wrong

When an egg cell is being formed, the cellular machinery which separates chromosomes is extremely imprecise at fishing them out of the cell's interior, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, ...

Why chemotherapy causes more infertility in women than in men

For a long time a relationship between infertility and chemotherapeutic agents has been assumed. Now, the mechanism has been elucidated. Mainly women are affected because the quality control in the oocytes is different from ...

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Oocyte

An oocyte, ovocyte, or rarely ocyte, is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC) which undergoes a mitotic division to form an oogonium. During oogenesis the oogonium becomes a primary oocyte (pronounced oh'a-site).

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