Understanding drivers of egg cell development

Northwestern Medicine scientists have identified how cytoskeletal proteins contribute to the growth of developing eggs in fruit flies, findings that further the field's understanding of how egg cells form and differentiate ...

Japanese researchers successfully induce primate oocytes in the lab

The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation ...

Study finds DNA repair declines with age, limiting fertility

Even worms have a ticking fertility clock. Older worms are less efficient at repairing broken DNA strands while making egg cells—part of a process that's essential for fertility. A new study from University of Oregon (UO) ...

Exploring flow transport in egg cells

Northwestern Medicine scientists discovered a new and unique transport mechanism within developing egg cells in fruit flies, according to a study published in eLife.

A missing 'motor' causes human eggs to fail

Human eggs often contain the wrong number of chromosomes, leading to miscarriages and infertility. A research team led by Melina Schuh at the Max Planck Institute (MPI) for Multidisciplinary Sciences has discovered that human ...

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Oocyte

An oocyte, ovocyte, or rarely ocyte, is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC) which undergoes a mitotic division to form an oogonium. During oogenesis the oogonium becomes a primary oocyte (pronounced oh'a-site).

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