Scientists who hunt for interesting bacterial metabolites using the online tool antiSMASH now have the opportunity to use an antiSMASH database with pre-calculated results of nearly 25,000 bacterial genomes. This database ...
Molecular & Computational biology
Nov 8, 2018
0
3
A new computational approach that allows the identification of molecular alterations associated with prognosis and resistance to therapy of different types of cancer was developed by the research group led by Nuno Barbosa ...
Molecular & Computational biology
Oct 4, 2018
0
59
Antibiotics have saved many lives by rescuing patients with bacterial or fungal infections, but these valuable drugs also have a dark side. As with most clinical drugs, many antibiotics can also have undesired effects on ...
Cell & Microbiology
Oct 1, 2018
0
219
An updated web server will improve analysis of genetic material. This will help researchers optimise bacteria for the industrial production of novel antibiotics, vitamins and food-related compounds.
Cell & Microbiology
Jul 12, 2018
0
4
Even living cells have their own tangled problems to solve. They involve knots that arise accidentally in DNA and that can comprise its functionality. Researchers now suggest that the DNA propensity to be supercoiled, just ...
Biochemistry
Jul 6, 2018
0
9
Biologists and chemists at the University of Konstanz have deciphered a molecular cellular mechanism related to the development of cancer. They report the interaction between the tumour-suppressor protein p53, known as the ...
Biotechnology
Jan 26, 2018
0
8
Mitochondria generate most of the energy cells need through a respiratory chain for which they must produce their own proteins. The research group of Associate Professor Henna Tyynismaa, University of Helsinki, Finland, has ...
Biochemistry
Dec 12, 2017
0
16
The endogenous protein RAGE, which has usually been negatively associated with chronic inflammation and diabetic complications, plays a major role in the repair of DNA damage—and also appears to heal tissue damaged as a ...
Biochemistry
Nov 28, 2017
0
155
Researchers at Karolinska Institutet have discovered that the protein complex RNase P in the cell's mitochondria behaves differently than previously thought. The findings, published in Nucleic Acids Research, give important ...
Cell & Microbiology
Oct 16, 2017
0
554
Scientists have developed a computational method to detect chemical changes in DNA that highlight cell diversity and may lead to a better understanding of cancer.
Biotechnology
Aug 4, 2017
0
179
