Microbes have been engineered as renewable cell factories for producing a vast array of products, such as pharmaceuticals, biofuels and bio-chemicals. However, static engineering strategies often result in metabolic imbalance, ...
Molecular & Computational biology
Aug 11, 2020
0
0
It is no secret that DNA, in the form of chromosomes, is the building block of life. Incorrect distribution of chromosomes during cell division can have disastrous consequences. Unbalanced chromosome copy, or aneuploidy, ...
Cell & Microbiology
Jun 24, 2020
0
114
Experimental data and computer simulations have yielded an innovative technique to characterize the configurations of an RNA molecule. The work, published in Nucleic Acids Research, opens new roads to studying dynamic molecular ...
Molecular & Computational biology
Jan 23, 2020
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7
Biology encodes information in DNA and RNA, which are complex molecules finely tuned to their functions. But are they the only way to store hereditary molecular information? Some scientists believe life as we know it could ...
Biochemistry
Nov 11, 2019
5
2961
For almost any conceivable protein, corresponding antibodies can be developed to block it from binding or changing shape, which ultimately prevents it from carrying out its normal function. As such, scientists have looked ...
Biotechnology
Nov 5, 2019
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187
Is there a solution to bacteria becoming resistant to antibiotics? One answer may be found by studying the world's largest and most brutal army, new University of Otago microbiology research shows.
Cell & Microbiology
Aug 29, 2019
0
181
Researchers from two University of Texas System institutions have engineered biological components that can rewire genetic response pathways, creating a template for designing new cellular behaviors with wide-ranging potential ...
Molecular & Computational biology
Jul 11, 2019
0
50
Today, thousands of databases with biological data are publicly available. They include data on gene and protein sequences and detailed measurements of different cellular parameters, such as the exact quantities of all proteins ...
Cell & Microbiology
Feb 5, 2019
0
42
An international research consortium, spearheaded by the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg, has developed a database that is unique in the world: the Virtual Metabolic Human ...
Molecular & Computational biology
Nov 14, 2018
0
7
Scientists who hunt for interesting bacterial metabolites using the online tool antiSMASH now have the opportunity to use an antiSMASH database with pre-calculated results of nearly 25,000 bacterial genomes. This database ...
Molecular & Computational biology
Nov 8, 2018
0
3
