New approach on the use of big data in clinical decision support

A new computational approach that allows the identification of molecular alterations associated with prognosis and resistance to therapy of different types of cancer was developed by the research group led by Nuno Barbosa ...

Gene cluster identification made easy through data mining

An updated web server will improve analysis of genetic material. This will help researchers optimise bacteria for the industrial production of novel antibiotics, vitamins and food-related compounds.

Supercoil me! The art of knotted DNA maintenance

Even living cells have their own tangled problems to solve. They involve knots that arise accidentally in DNA and that can comprise its functionality. Researchers now suggest that the DNA propensity to be supercoiled, just ...

Quality control is vital for the energy production of cells

Mitochondria generate most of the energy cells need through a respiratory chain for which they must produce their own proteins. The research group of Associate Professor Henna Tyynismaa, University of Helsinki, Finland, has ...

Endogenous protein reverses scarring in the lungs

The endogenous protein RAGE, which has usually been negatively associated with chronic inflammation and diabetic complications, plays a major role in the repair of DNA damage—and also appears to heal tissue damaged as a ...

Unexpected finding in the cell's power plant

Researchers at Karolinska Institutet have discovered that the protein complex RNase P in the cell's mitochondria behaves differently than previously thought. The findings, published in Nucleic Acids Research, give important ...

Flexible new method for early cancer diagnosis

Earlier discovery of cancer and greater precision in the treatment process are the objectives of a new method developed by researchers at Sahlgrenska Academy and Boston University. Investments are now being made to roll out ...

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