Related topics: stem cells · muscle · genes · cystic fibrosis · muscle cells

What's holding up CRISPR-based cures

The gene-editing tool called CRISPR that can quickly and cleanly remove specific pieces of DNA has revolutionized biotechnology. Many researchers believe the technique could end thousands of ailments. So what's needed to ...

New views of intracellular channel that controls skeletal muscle

Using high-resolution electron microscopy, Columbia University Medical Center (CUMC) researchers have uncovered new details of the structure and function of an intracellular channel that controls the contraction of skeletal ...

Engineering a permanent solution to genetic diseases

In his mind, Basil Hubbard can already picture a new world of therapeutic treatments for millions of patients just over the horizon. It's a future in which diseases like muscular dystrophy, cystic fibrosis and many others ...

Important regulation of cell invaginations discovered

Lack of microinvaginations in the cell membrane, caveolae, can cause serious diseases such as lipodystrophy and muscular dystrophy. Researchers at Lund University in Sweden have now discovered a "main switch" that regulates ...

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