Platelet transfusions are essential in managing bleeding and hemostatic dysfunction, and can be expanded to be used as cell therapy for a variety of diseases. The efforts to create such cell therapies require that researchers ...
A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target ...
Bio & Medicine
Dec 8, 2023
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A new molecular technology capable of binding to mRNA and regulating gene expression may offer a new avenue for treating diseases caused by haploinsufficiency, or the absence of one functional gene copy, according to a study ...
Biotechnology
Nov 17, 2023
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71
Autoimmune disorders are among the most prevalent chronic diseases across the globe. Emerging treatments for autoimmune disorders focus on "adoptive cell therapies," or those using cells from a patient's own body to achieve ...
Bio & Medicine
Nov 14, 2023
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A team of researchers at The University of Texas MD Anderson Cancer Center has developed a new method for using extracellular vesicles to enhance responses to immunotherapy in glioblastoma, potentially opening the door for ...
Bio & Medicine
Oct 19, 2023
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83
Identifying different types of body fluids can help forensic experts reconstruct a crime scene, but it's difficult to do so. In a study published in Electrophoresis, researchers developed a method using two different types ...
Molecular & Computational biology
Oct 18, 2023
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1
Messenger RNA (mRNA) vaccines are revolutionizing the therapy of cancer. They can be flexibly developed in a short period of time, allowing transient expression of multiple antigens for safe and efficient immunization. A ...
Bio & Medicine
Oct 16, 2023
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Researchers at Weill Cornell Medicine have illuminated one of the important ways that cells respond to stress. The findings could also be relevant to Alzheimer's, ALS and other diseases in which this mechanism may be abnormally ...
Cell & Microbiology
Sep 28, 2023
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Researchers at The University of Queensland are harnessing the latest sequencing technology developed by UK-based biotech Oxford Nanopore Technologies to analyze mRNA vaccines and therapies.
Bio & Medicine
Sep 21, 2023
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Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs).
