Before an egg becomes fertilized, sets of chromosomes must pair up to pass along genetic information. This happens within each reproductive cell, where separate chromosomes of male and female origin move toward each other ...
Cell & Microbiology
Jan 24, 2017
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325
(PhysOrg.com) -- DNA is under constant attack, from internal factors like free radicals and external ones like ionizing radiation. About 10 double-strand breaks – the kind that snap both backbones of the double helix ...
Cell & Microbiology
Apr 19, 2011
3
0
Cancer cells are resourceful survivors with plenty of tricks for staying alive. Researchers have uncovered one of these stratagems, showing how cells lacking the tumor suppressor BRCA1 can resume one form of DNA repair, sparing ...
Cell & Microbiology
Jan 21, 2013
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0
Many crustaceans, including lobster, crabs, and barnacles, have a cape-like shell protruding from the head that can serve various roles, such as a little cave for storing eggs, or a protective shield to keep gills moist.
Plants & Animals
Aug 1, 2022
0
291
The clustered regularly interspaced short palindrome repeats (CRISPR) and Crispr-associated protein 9 (CRISPR/Cas9) is now a well-known, revolutionary method to engineer microbial cells.
Double-strand breaks in DNA happen every time a cell divides and replicates. Depending on the type of cell, that can be pretty often. Many proteins are involved in everyday DNA repair, but if they are mutated, the repair ...
Cell & Microbiology
Feb 3, 2013
0
0
Dividing cells are prone to errors, and so they must be prepared to summon sophisticated emergency systems to deal with potential damage. One type of division-derailing mishap can occur when assault by certain chemicals causes ...
Cell & Microbiology
Aug 7, 2015
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793
The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 method can also result in unintended ...
Biotechnology
Sep 15, 2023
0
58
In a study published in Nucleic Acids Research, the team of cancer researcher Francis Rodier, an Université de Montréal professor, shows for the first time that cellular senescence, which occurs when aging cells stop dividing, ...
Cell & Microbiology
Nov 9, 2021
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218
Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, scientists have been working ...
Biotechnology
May 11, 2023
0
279
