Related topics: heart · heart failure · stem cells · heart attack · cells

New tool to accelerate drug discovery

Inside your body on the surface of cell membranes, a metaphorical communication and traffic network is underway as hormones—or chemical messengers—bind to cell membrane receptors to fine tune how the cell behaves. Once ...

Mutant stem cells defy rules of development

Imagine you're baking a cake, but you run out of salt. Even with the missing ingredient, the batter still looks like cake batter, so you stick it in the oven and cross your fingers, expecting to end up with something pretty ...

Investigating long-lived mitochondrial proteins

Northwestern Medicine investigators have discovered that a subset of proteins in mitochondria of brain and heart cells are long-lived, supporting the long-term stability of mitochondrial complex architecture.

Receptor location in heart plays a key role in their function

In the heart there are two different subtypes of beta-adrenergic receptors—beta1 and beta2—which are activated by the stress hormones adrenaline and noradrenaline. They both trigger the strongest stimulation of the heart ...

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