The shape of your heart matters

Curious to know if you're at risk for two common heart conditions? Your doctor may want to check the shape of your heart.

New tool identifies which cells will best repair muscles

Cells harvested from your own muscles could one day improve or even save your life if you are suffering from muscle loss after disease or an injury. The implantation of muscle cells offers an incredibly promising treatment ...

Simulating the shear destruction of red blood cells

Many medical devices for treating heart failure generate nonphysiological shear flow. This can trigger the destruction of red blood cells after implantation of ventricular assist devices (VADs), artificial heart valves, vascular ...

How heart failure disrupts the cell's mitochondria

Chronic heart failure causes the cell's powerhouses to malfunction, in part due to overconsumption of an important intermediary compound in energy production. Supplementing the diet to compensate for this could prove a promising ...

Low-cost disease diagnosis by mapping heart sounds

Aortic valve stenosis occurs when the aortic valve narrows, constricting blood flow from the heart through the artery and to the entire body. In severe cases, it can lead to heart failure. Identifying the condition can be ...

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Heart failure

Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest (see Terminology, below).

Common causes of heart failure include myocardial infarction and other forms of ischemic heart disease, hypertension, valvular heart disease and cardiomyopathy. Heart failure can cause a large variety of symptoms such as shortness of breath (typically worse when lying flat, which is called orthopnea), coughing, ankle swelling and reduced exercise capacity. Heart failure is often undiagnosed due to a lack of a universally agreed definition and challenges in definitive diagnosis. Treatment commonly consists of lifestyle measures (such as decreased salt intake) and medications, and sometimes devices or even surgery.

Heart failure is a common, costly, disabling and deadly condition. In developing countries, around 2% of adults suffer from heart failure, but in those over the age of 65, this increases to 6—10%. Mostly due to costs of hospitalization, it is associated with a high health expenditure; costs have been estimated to amount to 2% of the total budget of the National Health Service in the United Kingdom, and more than $35 billion in the United States. Heart failure is associated with significantly reduced physical and mental health, resulting in a markedly decreased quality of life. With the exception of heart failure caused by reversible conditions, the condition usually worsens with time. Although some patients survive many years, progressive disease is associated with an overall annual mortality rate of 10%.

This text uses material from Wikipedia, licensed under CC BY-SA