It is a fact that bacteria are increasingly developing antibiotic resistance. Information campaigns have raised awareness among the general public that the main cause of antibiotic resistance is the high 'selection pressure' ...
Molecular & Computational biology
Dec 10, 2021
0
42
A research team from the Universitat Autònoma de Barcelona (UAB) has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio ...
Molecular & Computational biology
Sep 10, 2021
0
34
Move over, gene-editing proteins—there's a smaller, cheaper, more specific genetic engineering tool on the block: DNAzymes—small DNA molecules that can function like protein enzymes.
Biochemistry
Jun 25, 2021
0
164
Scientists have developed polypeptide-based materials that act as effective vectors for delivering gene therapies. The first-of-its-kind platform enables the vectors to be adapted to suit the specific gene therapy cargo.
Bio & Medicine
Jun 9, 2021
0
7
As climate change continues to trigger the rise in temperature, increase drier conditions and shift precipitation patterns, adapting to new conditions will be critical for the long-term survival of most species. Researchers ...
Evolution
May 6, 2021
2
18
Adeno-associated viruses (AAVs) have become promising vehicles for delivering gene therapies to defective tissues in the human body because they are non-pathogenic and can transfer therapeutic DNA into target cells. However, ...
Biotechnology
Feb 11, 2021
0
90
University of Minnesota Twin Cities researchers in the Department of Chemistry have created a new polymer to deliver DNA and RNA-based therapies for diseases. For the first time in the industry, the researchers were able ...
Cell & Microbiology
Dec 18, 2020
0
359
A team of researchers from Children's Hospital of Philadelphia, the University of Pennsylvania, the University of North Carolina at Chapel Hill and Johns Hopkins School of Medicine has found evidence of genomic changes in ...
Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing ...
Cell & Microbiology
Sep 3, 2020
0
27
In experiments in rats and mice, two Johns Hopkins scientists—an engineer and an ophthalmologist—report the successful use of nanoparticles to deliver gene therapy for blinding eye disease. A uniquely engineered large ...
Bio & Medicine
Jul 7, 2020
0
69
