(PhysOrg.com) -- Gene therapy is medicine’s rising star with adeno-associated virus (AAV) vectors – nonpathogenic parvoviruses – among the most promising supporting actors, due largely to their capability to ...
The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job of knocking out genes to cure hereditary disease. But it's still not possible to insert whole genes ...
Biotechnology
Feb 20, 2024
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148
Researchers at Nanjing Normal University, China, have investigated the genetic underpinnings of mammalian longevity in search of new strategies to extend human lifespan.
Researchers have long been working on how to treat obesity, a serious condition that can lead to hypertension, diabetes, chronic inflammation, and cardiovascular diseases. Studies have also revealed a strong correlation of ...
Bio & Medicine
Dec 1, 2022
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362
Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.
Biotechnology
Nov 24, 2022
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738
Gene therapy using CRISPR/Cas9 gene editing is currently in clinical trials around the world for a variety of diseases. A report from Boston Children's Hospital, published June 27 in Nature Communications, warns of a potential, ...
Cell & Microbiology
Jul 6, 2022
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219
The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications ...
Cell & Microbiology
Jun 15, 2022
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136
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences in cells, and that detection ...
Biotechnology
Oct 28, 2021
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388
Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy. But CRISPR-Cas9 also has spawned other potentially powerful DNA manipulation tools that could help fix genetic ...
Biotechnology
Jul 30, 2020
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425
New tools for editing genetic code offer hope for new treatments for inherited diseases, some cancers, and even stubborn viral infections. But the typical method for delivering gene therapies to specific tissues in the body ...
Bio & Medicine
Sep 9, 2019
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160
Gene therapy is the insertion of genes into an individual's cells and tissues to treat a disease, such as a hereditary disease in which a deleterious mutant allele is replaced with a functional one. Although the technology is still in its infancy, it has been used with some success. Antisense therapy is not strictly a form of gene therapy, but is a genetically-mediated therapy and is often considered together with other methods.
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