Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)." These are ...
Cell & Microbiology
Jan 24, 2022
0
52
The COVID-19 pandemic highlighted the devastating impact of acute lung inflammation (ALI), which is part of the acute respiratory distress syndrome (ARDS) that is the dominant cause of death in COVID-19. A potential new route ...
Bio & Medicine
Dec 27, 2021
1
628
It is a fact that bacteria are increasingly developing antibiotic resistance. Information campaigns have raised awareness among the general public that the main cause of antibiotic resistance is the high 'selection pressure' ...
Molecular & Computational biology
Dec 10, 2021
0
42
A research team from the Universitat Autònoma de Barcelona (UAB) has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio ...
Molecular & Computational biology
Sep 10, 2021
0
34
Move over, gene-editing proteins—there's a smaller, cheaper, more specific genetic engineering tool on the block: DNAzymes—small DNA molecules that can function like protein enzymes.
Biochemistry
Jun 25, 2021
0
164
Scientists have developed polypeptide-based materials that act as effective vectors for delivering gene therapies. The first-of-its-kind platform enables the vectors to be adapted to suit the specific gene therapy cargo.
Bio & Medicine
Jun 9, 2021
0
7
As climate change continues to trigger the rise in temperature, increase drier conditions and shift precipitation patterns, adapting to new conditions will be critical for the long-term survival of most species. Researchers ...
Evolution
May 6, 2021
2
18
Adeno-associated viruses (AAVs) have become promising vehicles for delivering gene therapies to defective tissues in the human body because they are non-pathogenic and can transfer therapeutic DNA into target cells. However, ...
Biotechnology
Feb 11, 2021
0
90
University of Minnesota Twin Cities researchers in the Department of Chemistry have created a new polymer to deliver DNA and RNA-based therapies for diseases. For the first time in the industry, the researchers were able ...
Cell & Microbiology
Dec 18, 2020
0
359
A team of researchers from Children's Hospital of Philadelphia, the University of Pennsylvania, the University of North Carolina at Chapel Hill and Johns Hopkins School of Medicine has found evidence of genomic changes in ...
