In a paper in Cell Reports, Anindya Dutta, M.D., Ph.D., and colleagues detail the first structure-function study of a long non-coding RNA, or lncRNA, called MUNC lncRNA. Their findings point out the importance of experimentally ...
Cell & Microbiology
Feb 22, 2022
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A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge could be used for investigating cancers and other genetic diseases.
Biotechnology
Feb 21, 2022
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132
A new method that can induce interactions between specifically chosen locations on the genome allows researchers to begin to identify the causal relationship between three-dimensional chromosome structure and genome function. ...
Cell & Microbiology
Feb 18, 2022
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50
Stem cells are one of the few cell types within the body that have the ability to both self-renew and produce cells that develop into more specialized cell types which eventually built up a functional organ. During development, ...
Cell & Microbiology
Feb 15, 2022
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4
In an article in the Science, researchers at Uppsala University show how a DNA-binding protein can search the entire genome for its target sequence without getting held up on the way. The result contradicts our current understanding ...
Molecular & Computational biology
Jan 27, 2022
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60
Depending on the outcome of social conflicts, ants of the species Harpegnathos saltator do something unusual: they can switch from a worker to a queen-like status known as gamergate. Now, researchers reporting in the journal ...
Plants & Animals
Nov 4, 2021
0
65
Roughly one in every 1,000 individuals worldwide suffers from a ciliopathy. Symptoms include visual impairment, loss of hearing, obesity, kidney diseases, intellectual disabilities, and many other—in some cases serious—disorders, ...
Cell & Microbiology
Nov 4, 2021
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29
A CRISPR-Cas9 variant with deactivated DNA-cutting function—known as "dCas9"—is a powerful tool to help researchers understand what genes do when their expression is dialed up or down, but it has some limitations.
Molecular & Computational biology
Aug 4, 2021
0
13
St. Jude scientist Vibhor Mishra, Ph.D., is homing in on the location where important processes in gene regulation occur, and where single-stranded transcripts are converted into double-stranded RNAs (dsRNAs).
Cell & Microbiology
Jul 28, 2021
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8
The sensory cells in the inner ear and the touch receptors in the skin actually have a lot in common, according to a new study from the USC Stem Cell laboratory of Neil Segil published in the Proceedings of the National Academy ...
Cell & Microbiology
Jul 12, 2021
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