High-order chromatin structure is a prerequisite for the function of cis-regulatory elements in the genome, which plays an important role in gene regulation. In eukaryotes, the organization of the three-dimensional (3D) genome ...
Molecular & Computational biology
Feb 7, 2023
0
3
Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work—until now.
Biotechnology
Jan 23, 2023
0
77
The study of microRNAs (miRNAs), small RNAs that play important roles in gene regulation in animals and humans alike, have long been a topic of research interest. How these miRNAs control and regulate gene expression is believed ...
Molecular & Computational biology
Jan 20, 2023
0
12
A fundamental principle of molecular biology governs how proteins are made within the cell, which happens in two stages called transcription and translation. During transcription, information stored in DNA is copied into ...
Cell & Microbiology
Dec 22, 2022
0
29
DNA methylation is a biological process through which methyl groups are added to the DNA (genetic material). It is used as an epigenetic, i.e., a non-genetic strategy by prokaryotes to perform an array of functions such as ...
Cell & Microbiology
Dec 7, 2022
0
10
NASA's Artemis I launch is a major step forward in humans going deeper and spending longer in space than ever before.
Space Exploration
Nov 16, 2022
2
3
Scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Institute for Molecular Infection Biology (IMIB) in Würzburg want to better understand how the oral cavity germ Fusobacterium nucleatum ...
Cell & Microbiology
Nov 3, 2022
0
14
Yeast, that simple organism essential to making beer and bread, has revealed for Cornell University researchers a key mechanism in how genes are controlled.
Cell & Microbiology
Oct 27, 2022
0
5
Recent studies have shown that liquid-liquid phase separation—akin to how oil droplets form in water—leads to formation of diverse types of membraneless organelles, such as stress granules and nucleoli, in living cells. ...
Cell & Microbiology
Oct 21, 2022
0
17
For four decades, Specificity Protein 1 (Sp1) has been cast solely as a transcription factor, a type of protein that binds DNA and turns genes on. But a Donnelly Center study has now revealed that Sp1 plays another unexpected ...
Cell & Microbiology
Sep 6, 2022
0
34
