Nature is filled with extraordinarily precise molecular shapes that fit together like a hand in glove. Proteins, for example, can assemble into a wide variety of well-defined shapes that grant them their function.
Bio & Medicine
14 hours ago
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34
Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as "organelles." Tracing their genesis and determining their structure is fundamental to understanding cell function ...
Cell & Microbiology
Apr 10, 2024
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124
University of Michigan researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.
Cell & Microbiology
Apr 8, 2024
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44
Researchers studying the role of proteins in health and disease use experimental tools that inactivate proteins, destroy them, or prevent them from being made in cells. In one approach, they mark targeted proteins with "destroy ...
Biotechnology
Mar 15, 2024
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52
Many proteins within the body form complexes with other proteins, determining the fate of cells. Therefore, the analysis of protein-protein interactions (PPI) is a crucial process for understanding the biological function ...
Cell & Microbiology
Feb 22, 2024
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5
A new study published in Nature Communications from researchers at Karolinska Institutet solves a long-standing problem by establishing a system that allows site-specific protein degradation within mitochondria, the cellular ...
Cell & Microbiology
Feb 21, 2024
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23
New research from the Weeks Lab in the Department of Biochemistry opens the door for scientists to explore cell death, a critical biochemical process, with greater ease.
Cell & Microbiology
Feb 20, 2024
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45
When an enemy invades, defenders are ferried to the site to neutralize the marauders. In the human body, a protein carrier called SPNS2 transports S1P molecules from endothelial cells to rally immune cell response in infected ...
Cell & Microbiology
Feb 15, 2024
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41
A new artificial intelligence (AI) tool that draws logical inferences about the function of unknown proteins promises to help scientists unravel the inner workings of the cell.
Molecular & Computational biology
Feb 14, 2024
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217
In a groundbreaking study, researchers have unveiled a previously unknown conformational state of a crucial transporter protein, OxlT, which plays a vital role in preventing kidney stone formation. This discovery, achieved ...
Biochemistry
Jan 29, 2024
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46
