CRISPR-based gene editing has potential therapeutic benefits but also some technical shortcomings. One set of these gene editing tools, base editors, can rewrite the four individual DNA letters, or bases— A, C, T or G—which ...
Biotechnology
Feb 11, 2020
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26
A research team led by Profs. Gao Caixia and LI Jiayang from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have engineered five saturated targeted endogenous mutagenesis editors (STEMEs) ...
Plants & Animals
Jan 13, 2020
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112
In a study published in Nature on June 10, researchers from Dr. Yang Hui's Lab at the Institute of Neuroscience of the Chinese Academy of Sciences (CAS), and collaborators from the CAS-MPG Partner Institute for Computational ...
Biotechnology
Jun 10, 2019
2
147
A team of researchers with the Broad Institute of Harvard and MIT has found evidence showing that using base editors can lead to unexpected RNA cellular edits. In their paper published in the journal Science Advances, the ...
Researchers at the Center for Genome Engineering, within the Institute for Basic Science (IBS, South Korea) have identified the mistake rate of DNA editing tools known as adenine base editors, which are based on CRISPR. Assessing ...
Biotechnology
Mar 5, 2019
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17
Chinese scientists have found that cytosine base editors (BE3 and HF1-BE3) induce genome wide off-target mutations.
Biotechnology
Feb 28, 2019
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101
(Phys.org)—Online chemistry journal Synlett, which is published by Thieme, has tested the idea of intelligent crowd reviewing of scientific papers. The project was the brainchild of Benjamin List, a journal editor (and ...
Researchers at the Institute of Basic Science (IBS) proved the accuracy of a recently developed gene editing method. This works as "DNA scissors" designed to identify and substitute just one nucleotide among the 3 billion. ...
Biotechnology
Apr 11, 2017
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183
What have plant scientists learned in the laboratory in the past three to five years that could be used to reduce inputs of water, chemical fertilizers and herbicides to agricultural fields?
Biotechnology
Sep 16, 2016
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12
A computer algorithm being developed by Brown University researchers enables users to instantly change the weather, time of day, season, or other features in outdoor photos with simple text commands. Machine learning and ...
Computer Sciences
Aug 8, 2014
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