Gene therapy using CRISPR/Cas9 gene editing is currently in clinical trials around the world for a variety of diseases. A report from Boston Children's Hospital, published June 27 in Nature Communications, warns of a potential, ...
Cell & Microbiology
Jul 6, 2022
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Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy. But CRISPR-Cas9 also has spawned other potentially powerful DNA manipulation tools that could help fix genetic ...
Biotechnology
Jul 30, 2020
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425
A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology—CRISPR-Cas9 and a reverse transcriptase—into a ...
Biotechnology
Oct 21, 2019
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Using a technique that can precisely edit DNA bases, MIT researchers have created a way to store complex "memories" in the DNA of living cells, including human cells.
Biotechnology
Aug 22, 2019
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A team of researchers from the Broad Institute, Harvard and Boston's Children's Hospital has developed a new way to improve the editing efficiency of base editors using a system called "phage assisted continuous evolution ...
A Massachusetts General Hospital (MGH) research team reports that several of the recently developed CRISPR base editors, which create targeted changes in a single DNA base, can induce widespread off-target effects in RNA, ...
Biotechnology
Apr 17, 2019
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An international team of researchers has succeeded in making 13,200 edits to a single cell—and the cell survived. In their paper uploaded to the bioRxiv preprint server, the team describes the edits they made, how they ...
(Phys.org)—A research team made up of members from France, Canada and the US has been studying the manuscript submission and rejection process for biologically based papers submitted to journals for publication. They have ...
(PhysOrg.com) -- The findings of a Spanish study claiming that Wikipedia's editors are leaving at an alarming rate have been refuted by the Wikimedia Foundation and by Wikipedia co-founder Jimmy Wales.
By analyzing the results of many prior studies on the use of screen-based technologies by children, an international team of psychologists and human biomechanics researchers has found mixed outcomes. In their study, reported ...
