A strategy to refine genetic base editors
Want to keep the riffraff out of the gene pool party? Sneak in and slam the gate before they arrive.
Want to keep the riffraff out of the gene pool party? Sneak in and slam the gate before they arrive.
Biotechnology
Nov 11, 2021
0
36
Targeted mutations to the genome can now be introduced by splitting specific mutator enzymes and then triggering them to reconstitute, according to research from the Perelman School of Medicine at the University of Pennsylvania. ...
Biochemistry
Oct 28, 2021
0
674
A team of researchers from Verve Therapeutics and the Perelman School of Medicine at the University of Pennsylvania has developed a CRISPR gene-editing technique that lowered the levels of cholesterol in the blood of test ...
A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause ...
Biotechnology
Mar 11, 2021
0
284
For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a ...
Evolution
Nov 18, 2020
0
45
Biomolecular engineers at Rice University have found a C-worthy technique that dramatically enhances the accuracy of gene editing.
Molecular & Computational biology
Jul 15, 2020
0
108
Gene editing technology is getting better and growing faster than ever before. New and improved base editors—an especially efficient and precise kind of genetic corrector—inch the tech closer to treating genetic diseases ...
Biotechnology
Jun 12, 2020
0
97
Many genetic and breeding studies have shown that point mutations and indels (insertions and deletions) can alter elite traits in crop plants. Although nuclease-initiated homology-directed repair (HDR) can generate such changes, ...
Biotechnology
Mar 16, 2020
0
32
The editors at the journal Scientific Reports have retracted a paper that was published last summer challenging the human factor in climate change. In their retraction notice, the editors cited concerns about the paper regarding ...
With a new CRISPR gene-editing methodology, scientists from the University of Illinois at Urbana-Champaign inactivated one of the genes responsible for an inherited form of amyotrophic lateral sclerosis—a debilitating and ...
Biotechnology
Feb 24, 2020
0
379