St. Jude Children's Research Hospital investigators have developed software to shrink the error rate in next-generation sequencing data by as much as 100-fold, which would likely speed early detection of relapse and other ...
Biotechnology
Mar 14, 2019
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16
A team of researchers from the Wang Yangming Laboratory at Peking University's College of Future Technology has recently identified a DddA homolog from Simiaoa sunii (Ddd_Ss) that can efficiently deaminate cytosine in DC ...
Biotechnology
Feb 20, 2023
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5
A new tool to predict the chances of successfully inserting a gene-edited sequence of DNA into the genome of a cell, using a technique known as prime editing, has been developed by researchers at the Wellcome Sanger Institute. ...
Biotechnology
Feb 16, 2023
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17
DNA nanotechnology—the research field using DNA molecules as building material—has developed rapidly during recent years and enabled the construction of increasingly complex nanostructures. DNA nanostructures, such as ...
Bio & Medicine
Mar 1, 2021
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14
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health, have demonstrated that DNA previously thought to be "junk" plays a critical role ...
Cell & Microbiology
Dec 11, 2012
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0
Genome assembly projects are costly in both time and money; where identifying problems with your data post-assembly can be a real setback. With the K-mer Analysis Toolkit (KAT), researchers can access and confirm their results ...
Biotechnology
Dec 5, 2016
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2
Base editors, which enable production of highly efficient targeted point mutations in genomic DNA without causing double-stranded DNA breaks, hold great promise for gene therapy in human disease and trait improvement in crop ...
Biotechnology
Jul 27, 2020
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5
A microscopic species of algae is causing toxic algal blooms around the world, affecting two dozen states in the U.S., especially Texas. New research into the genetic diversity of the responsible organism, Prymnesium parvum, ...
Ecology
Aug 14, 2023
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2
The DNA molecule is not naked in the nucleus. Instead, it is folded in a very organized way by the help of different proteins to establish a unique spatial organization of the genetic information. This 3D spatial genome organization ...
Cell & Microbiology
Apr 15, 2021
0
59
In the course of optimizing key procedures of genome editing, researchers from the department of Developmental Biology / Physiology at the Center for Organismal Studies of Heidelberg University have succeeded in substantially ...
Biotechnology
Jan 24, 2023
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