The next computer: your genes

(PhysOrg.com) -- "Human beings are more or less like a computer," Jian-Jun Shu tells PhysOrg.com. "We do computing work, and our DNA can be used in computing operations." Shu is a professor at the School of Mechanical and ...

New understanding of CRISPR-Cas9 tool could improve gene editing

Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy. But CRISPR-Cas9 also has spawned other potentially powerful DNA manipulation tools that could help fix genetic ...

CRISPR base editors can induce wide-ranging off-target RNA edits

A Massachusetts General Hospital (MGH) research team reports that several of the recently developed CRISPR base editors, which create targeted changes in a single DNA base, can induce widespread off-target effects in RNA, ...

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