How a viral RNA changes shape to hijack host cells

University of Colorado Anschutz Medical Campus researchers have observed how an RNA molecule from a virus forms a complex, three-dimensional structure, and is able to change its shape to hijack host proteins. The details ...

Improvements in microscopy home in on biology's elusive details

In the late 1600s, the Dutch tradesman Anthoni van Leeuwenhoek began investigating the world of the very small using the first microscope, discovering a riotous world of protists, bacteria, and other previously unseen organisms. ...

Support film makes cryo-electron microscopy sharper

A trio of researchers at MRC Laboratory of Molecular Biology has developed a support film for creating sharper images in cryo-electron microscopy. In their paper published in the journal Science, Katerina Naydenova, Peipei ...

New techniques probe vital and elusive proteins

The number of proteins in the human body, collectively known as the proteome, is vast. Somewhere between 80,000 and 400,000 proteins circulate in our cells, tissues and organs, carrying out a broad range of duties essential ...

Researchers map structure of key chromatin-remodeling complex

Northwestern University researchers have mapped a group of proteins that play a critical role in both gene expression and repairing damaged DNA. By understanding this protein complex, called SWI/SNF, researchers hope to better ...

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