A recent study from the University of Eastern Finland shows that genetic variation determines chromatin accessibility and the binding of transcription factors. Chromatin consists of DNA and proteins attached to it. The density ...
Molecular & Computational biology
Jan 22, 2024
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5
Just as healthy organs are vital to our well-being, healthy organelles are vital to the proper functioning of the cell. These subcellular structures carry out specific jobs within the cell; for example, mitochondria power ...
Cell & Microbiology
Jan 1, 2024
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121
According to textbooks, proteins work by folding into stable 3D shapes that, like Lego blocks, precisely fit with other biomolecules.
Cell & Microbiology
Oct 2, 2023
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136
A new study led by University of Maryland physicists sheds light on the cellular processes that regulate genes. Published in the journal Science Advances, the paper explains how the dynamics of a polymer called chromatin—the ...
Molecular & Computational biology
Aug 15, 2023
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11
In 1983, scientists discovered hexasomes—a unique molecular structure that helps cells package their DNA. Now, a study conducted by the Eustermann group at EMBL Heidelberg has shed light on how DNA packaging into hexasomes ...
Cell & Microbiology
Jul 13, 2023
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1
The tumor suppressor protein p53 has been dubbed the "guardian of the genome" because it protects the DNA from stress or long-term damage by regulating the expression of numerous genes involved DNA repair, cell division and ...
Molecular & Computational biology
Jun 30, 2023
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50
Scientists studying cells have long held the view that euchromatin, the part of chromatin that is made up of genes and is genetically active, is open and can be transcribed. A research team, looking at new evidence from genomics ...
Cell & Microbiology
Jun 27, 2023
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5
A research team led by Dr. Gary Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong (HKU), has revealed the function of a unique enzyme, ANKLE1. ANKLE1 acts on chromatin bridges that are trapped ...
Cell & Microbiology
Apr 18, 2023
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370
The DNA molecule is located in the cell nucleus as a densely packed complex of DNA and protein, known as chromatin. Wrapped in sections around a core of special proteins known as histones, the DNA forms so-called nucleosomes, ...
Cell & Microbiology
Apr 6, 2023
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41
Studying the microbiology of any entity, be it a molecule or a dolphin, ideally means putting a spotlight as close to the source material as possible. That can be especially challenging when you're investigating the Rube ...
Biochemistry
Apr 5, 2023
0
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