Argonaute proteins help fine-tune gene expression
A nuclear protein bound to RNA molecules affects chromatin structure and gene expression.
Biotechnology
Oct 28, 2019
0
7
News tagged with chromatin
Recipe for making a fruitfly
Researchers have used mass spectroscopy to determine the absolute copy numbers of nuclear proteins and histone modifications in the Drosophila embryo. The results provide new insights into the mechanisms of animal development.
Plants & Animals
Oct 22, 2019
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4
Scientists unwind mystery behind DNA replication
The molecules of life are twisted. But how those familiar strands in DNA's double helix manage to replicate without being tangled up has been hard to decipher. A new perspective from Cornell physicists is helping unravel ...
Molecular & Computational biology
Oct 17, 2019
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76
A catalog of DNA replication proteins
Maintenance of genome integrity—and prevention of diseases such as cancer—requires complete and faithful replication of the genome every cell division cycle.
Biotechnology
Oct 4, 2019
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11
Mathematical modeling shows why animals see at night
Nocturnal and diurnal mammals see the same—but only for a brief time. When mice are born, the chromatin in the cells of their eyes has a diurnal structure. Day by day, the layout of this chromatin slowly inverts, allowing ...
Molecular & Computational biology
Sep 11, 2019
0
212
Does rearranging chromosomes affect their function?
Molecular biologists have long thought that domains in the genome's 3-D organization control how genes are expressed. After studying highly rearranged chromosomes in fruit flies, EMBL researchers now reveal that while this ...
Cell & Microbiology
Jul 15, 2019
0
124
Unraveling the three-dimensional genomic structure of male germ cells
The genome is not just a linear sequence of letters, but is also compartmentalized into a specifically tailored chromatin structure within cell nuclei. This three-dimensional genomic structure is fundamental, given that it ...
Cell & Microbiology
Jul 10, 2019
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0
A model to decipher the complexity of gene regulation
How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...
Molecular & Computational biology
May 2, 2019
0
91
uliCUT&RUN maps protein binding on chromatin in single cells and single embryos
Groundbreaking research by Sarah Hainer, an assistant professor of gene expression and cell fate in the University of Pittsburgh Department of Biological Sciences, and Thomas G. Fazzio of the University of Massachusetts Medical ...
Cell & Microbiology
Apr 8, 2019
0
5
Russian scientists discover a new function of the nucleus lamina proteins
A group of Russian scientists has discovered a new function of nuclear lamina (NL) proteins: to arrange the genetic material inside cells. Understanding the mechanisms involved in gene packaging will help researchers to control ...
Cell & Microbiology
Apr 4, 2019
0
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