A group of Russian scientists has discovered a new function of nuclear lamina (NL) proteins: to arrange the genetic material inside cells. Understanding the mechanisms involved in gene packaging will help researchers to control ...
Cell & Microbiology
Apr 4, 2019
0
14
A study by the University of Liverpool reveals new insights into how cells respond to oxygen deprivation.
Cell & Microbiology
Mar 20, 2019
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21
Researchers in Japan have discovered that the DNA inside human cells moves around less when its genes are active. The study, which will be published March 1 in the Journal of Cell Biology, suggests that RNA polymerase II ...
Cell & Microbiology
Mar 1, 2019
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15
A new study based on electron microscopy techniques at low temperatures demonstrates that during mitosis, chromosome DNA is packed in stacked layers of chromatin. The research, published in EMBO Journal, confirms a surprising ...
Cell & Microbiology
Jan 9, 2019
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188
Scientists at Kyushu University and Tokyo Institute of Technology in Japan have developed a technique that enables analysis of DNA-protein interactions using very small numbers of cells, ranging from 100 to 1,000. Their method ...
Cell & Microbiology
Dec 12, 2018
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58
Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death ...
Cell & Microbiology
Nov 7, 2018
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9
LMU researchers have, for the first time, systematically determined the positioning of the packing units of the fruit fly genome and discovered a new protein that defines their relationship to the DNA sequence.
Plants & Animals
Nov 5, 2018
0
11
DNA flows inside a cell's nucleus in a choreographed line dance, new simulations reveal. The finding is the first large-scale explanation of genetic material moving within a working cell.
Molecular & Computational biology
Oct 25, 2018
2
257
In the cell nucleus, the genomic DNA is packaged into a tightly condensed form, which is referred to as chromatin. The basic unit of chromatin organization is the nucleosome, a DNA-protein complex consisting of a defined ...
Cell & Microbiology
Sep 4, 2018
0
11
In eukaryotic cells, linear genetic DNA wraps around histones to form stable nucleosomes that further assemble to form chromatins. Nucleosomes represent big barriers to the transcription machine RNA polymerase.
Cell & Microbiology
Jul 23, 2018
0
11
