Two research teams led by Professors Brian Luke and Helle Ulrich at the Institute of Molecular Biology have deciphered how two enzymes, RNase H2 and RNase H1, are coordinated to remove RNA-DNA hybrid structures from chromosomes. ...
Molecular & Computational biology
Nov 27, 2019
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The final stage of DNA replication—"termination"—occurs when two DNA copy machines advance upon each other and unwind the final stretch of DNA. This process occurs about 60,000 times per human cell cycle and is crucial ...
Cell & Microbiology
Oct 28, 2019
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Maintenance of genome integrity—and prevention of diseases such as cancer—requires complete and faithful replication of the genome every cell division cycle.
Biotechnology
Oct 4, 2019
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Stomata are plant-specific epidermal structures that consist of paired guard cells surrounding a pore. The opening and closing of these micro-valves facilitate carbon dioxide uptake for photosynthesis and reduce excessive ...
Molecular & Computational biology
Aug 21, 2019
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The body's cells are constantly dividing—which, somewhat counterintuitively, means that they're constantly multiplying. Because when a cell divides it doesn't split into two useless halves, but rather into two fully functional ...
Cell & Microbiology
Aug 8, 2019
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A gene called MYC has become one of the hottest targets for cancer researchers around the world. MYC is known to drive tumor growth in nearly all cancer types—but successfully targeting the gene has proven to be a challenge. ...
Biochemistry
Jul 8, 2019
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For biologists everywhere, April 25 is auspicious. It is DNA Day and commemorates the date in 1953 when scientists Francis Crick, Rosalind Franklin, James Watson and Maurice Wilkins published seminal scientific papers describing ...
Cell & Microbiology
Apr 26, 2019
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If asked about clones, most people think of evil sci-fi characters. However, in real life, the word "clone" often has broader, far more positive applications. Just as office workers replicate documents by using copy machines, ...
Biotechnology
Oct 8, 2018
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Researchers from Osaka University in Japan have uncovered a key control mechanism of DNA replication with potential implications for better understanding how cells maintain genetic information to prevent diseases or cancer.
Cell & Microbiology
Aug 16, 2018
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Cells propagate by making copies of themselves via genome replication. Arguably, replication of DNA is the most fundamental and conserved mechanism of all life forms. Cracking the secret of how this process is achieved with ...
Biochemistry
Jul 6, 2018
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