In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes ...
Biochemistry
May 3, 2024
0
30
Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells—they give rise to rapidly dividing progenitor cells, which in turn ...
Cell & Microbiology
Apr 30, 2024
0
60
It has been more than 40 years since the beginning of the HIV/AIDS epidemic and scientists still don't fully understand how HIV enters and replicates in human cells, which has hindered the development of treatments.
Cell & Microbiology
Apr 30, 2024
0
1
Engineered protein filaments originally produced by bacteria have been modified by scientists to conduct electricity. In a study published recently in the journal Small, researchers revealed that protein nanowires—which ...
Bio & Medicine
Apr 29, 2024
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163
Pyroptosis is a type of programmed cell death mediated by the gasdermin (GSDM) protein family, which plays important roles in the body's defense against pathogen infection, elimination of abnormal or harmful cells, and other ...
Cell & Microbiology
Apr 29, 2024
0
23
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers ...
Biochemistry
Apr 25, 2024
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54
Cells buzz with millions of different biomolecules that diffuse chaotically through their substructures, yet they manage to ensure exquisite functional and spatial specificity.
Cell & Microbiology
Apr 24, 2024
0
11
LMU researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy.
Molecular & Computational biology
Apr 24, 2024
0
25
In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins—essential building blocks of life—to create cells that ...
Biochemistry
Apr 23, 2024
0
144
Through years of engineering gene-editing systems, researchers have developed a suite of tools that enable the modification of genomes in living cells, akin to "genome surgery." These tools, including ones based on a natural ...
Cell & Microbiology
Apr 22, 2024
0
40
