Protein aggregates are toxic for mitochondrial function, and thus disrupt the supply of chemical energy to their host cells. An LMU team has characterized a protein complex that prevents the build-up of such deposits in the ...
Cell & Microbiology
Jun 24, 2019
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1
Engineered T cell immunotherapy, such as chimeric antigen receptor T cell (CAR-T) and T cell receptor T cell (TCR-T) therapy, has emerged as a potent therapeutic strategy for treating tumors.
Biochemistry
Apr 15, 2019
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10
During brain development, billions of neuron nerve cells must find their accurate pathway in the brain in order to form trillions of neuronal circuits enabling cognitive, sensory and emotional wellbeing. To achieve this remarkable ...
Cell & Microbiology
Mar 7, 2019
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10
More than 70 percent of researchers failed to reproduce another scientist's experiment, according to a survey conducted by Nature in 2016. If scientists can't reproduce each other's work, important discoveries may never leave ...
Cell & Microbiology
Feb 19, 2019
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7
A new optical microscope system called stimulation and imaging-based functional optical microscopy (SIFOM) can stimulate multiple cells simultaneously via a holographic method and monitor cell activity after the stimulation ...
Optics & Photonics
Jan 28, 2019
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4
Scientists at the Okinawa Institute of Science and Technology Graduate University (OIST) have resolved a fundamental weakness in a promising solar technology known as Perovskite Solar Cells, or PSCs. Their innovations appear ...
Energy & Green Tech
Jan 22, 2019
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14
Scientists at Newcastle University have developed a biological system which lets cells form a desired shape by moulding their surrounding material—in the first instance creating a self-curving cornea.
Biochemistry
Jan 17, 2019
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32
Liver-on-a-chip cell culture devices are attractive biomimetic models in drug discovery, toxicology and tissue engineering research. To maintain specific liver cell functions on a chip in the lab, adequate cell types and ...
Microbial communities residing within the gut have been implicated in several aspects of health and disease. The mammalian gut microbiome, for example, not only influences metabolic functions and immune responses, but has ...
Plants & Animals
Jan 15, 2019
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3
A mechanically compromised skull can result from enlarged fontanelles and smaller frontal bones due to defective migration and differentiation of osteoblasts in the skull primordia (developing skull). The Wnt/Planar cell ...
