Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early time points. For this ...
Cell & Microbiology
Dec 9, 2022
0
28
A team of researchers writing in the journal Angewandte Chemie has developed a bioorthogonal molecular system for the targeted introduction of nitrite ions into cells. Their system releases nitrite ions in cancer cells using ...
Biochemistry
Nov 25, 2022
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31
Mitochondrial Ca2+ ions are crucial regulators of bioenergetics and cell death pathways. Essential in this context are so-called Ca2+ transporters. In recent decades, the major players responsible for mitochondrial Ca2+ uptake ...
Cell & Microbiology
Nov 25, 2022
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35
Oxygen profoundly affects the physiology of aerobic organisms through multiple mechanisms. Inadequate oxygen availability (hypoxia) can lead to cellular dysfunction and even cell death.
Cell & Microbiology
Nov 25, 2022
0
2
Mitochondria are primarily known as the powerhouse of the cell. However, these cellular organelles are required not only for providing energy: Professor Konstanze Winklhofer and her group at the Faculty of Medicine at Ruhr ...
Cell & Microbiology
Nov 17, 2022
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21
A team of researchers at Umeå University has discovered that an enzyme in human cells has probably evolved from an ancient single-celled organism. The enzyme's unique properties mean that it could be used as a building block ...
Evolution
Nov 7, 2022
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1031
Researchers at Europe's science lab CERN, who regularly use particle physics to challenge our understanding of the universe, are also applying their craft to upend the limits to cancer treatment.
Plasma Physics
Oct 22, 2022
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177
As researchers glean new insights into the dynamic inner world of the human immune system, it has become increasingly clear that mitochondria are critical regulators of how our bodies respond to disease.
Cell & Microbiology
Oct 21, 2022
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91
Mitochondria—the organelles responsible for energy production in human cells—were once free-living organisms that found their way into early eukaryotic cells over a billion years ago. Since then, they have merged seamlessly ...
Cell & Microbiology
Oct 20, 2022
0
69
The Black Death was the single greatest mortality event in recorded history, killing up to 50% of the European population in less than five years. New research from the University of Chicago, McMaster University, and the ...
Evolution
Oct 19, 2022
0
126
