The ability to self-repair damaged tissue is one of the key features that define living organisms. Plants in particular are regeneration champions, a quality that has been used for centuries in horticultural techniques such ...
Biotechnology
Nov 2, 2016
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Humans pride themselves on being able to multitask, especially under pressure. But it turns out that we aren't the only ones who are organized: Researchers from Japan have discovered that plants balance genome maintenance ...
Evolution
Jun 16, 2021
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9
DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species. To detect and repair DNA lesions, cells have evolved DNA damage response. ...
Cell & Microbiology
Feb 27, 2019
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Researchers at Karolinska Institutet, Sweden, and the University of Sussex, England, have discovered that the process of copying DNA generates a brake signal that stalls cell division. This molecular brake ensures that the ...
Cell & Microbiology
Jun 28, 2018
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3
A new bioinformatics tool, MHcut, developed by researchers in Kyoto, Japan, and Montreal, Canada, reveals that a natural repair system for DNA damage, microhomology-mediated end joining, is probably far more common in humans ...
Biotechnology
Oct 28, 2019
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5
Some DNA repair enzymes can become double-edged swords - If they work too slowly, they can block necessary cell maintenance and contribute to cell death. This could explain the somewhat mysterious success of the widely used ...
Cell & Microbiology
Apr 28, 2009
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Recent work from Carnegie's Chenhui Wang and Allan Spradling reveals a surprising capability of renal stem cells in fruit flies—remodeling. Their work, which could eventually guide kidney stone treatments, was published ...
Cell & Microbiology
Jun 16, 2022
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22
A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics. Their findings provide new insights into chromosomal ...
Cell & Microbiology
Apr 19, 2023
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21
The Wip1 protein is important for survival, but mutations that inactivate it carry some surprising features. "A lack of Wip1 results in an excessive immune reaction to infectious organisms, in some cases killing the host," ...
Cell & Microbiology
Dec 19, 2012
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0
Two phases of the cell cycle of human embryonic stem cells have been shown, for the first time, to actively employ pathways that maintain pluripotency—the potential to develop into almost any type of cell in the body.
Cell & Microbiology
Nov 4, 2015
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