A bacterial toxin that acts as a mediator rather than a killer

Traditionally, bacterial toxins have been seen as killers of target cells. But is there more than meets the eye? Umeå University Professor Teresa Frisan and her team have discovered that toxin-host interactions are more ...

Cryo-EM reveals how '911' molecule helps fix damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.

Measuring the hardness of living tissues without damage

When a fertilized egg is developing into a fetus, cell populations forming tissues are in a fluid state, and thus, the tissue can be easily deformed. Cells also generate mechanical forces during development that contribute ...

One, two, four, eight – lessons from dividing cells

The IMCB was established in 1987 at the National University of Singapore before becoming an autonomous research institute of A*STAR and moving to Biopolis in 2004. The IMCB strives to maintain the scientific excellence of ...

A hair-trigger for cells fighting infection

To fight infections cells in the immune system play a dangerous game with their own genes. Damaging genes allows B cells to make antibodies that are specifically equipped to target to specific causes of illness, but damaging ...

page 27 from 29