Repair of DNA lesions is essential for mammalian development. Notably, DNA lesions in cells caused by genotoxic agents results in arrest of cell cycle and ultimately in cell death. In response, DNA polymerase ζ (Polζ) is ...
Biochemistry
Jun 25, 2014
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People have them, cats have them and whales have some, too. Neurons, those interlinked nerve cells that carry sensations including pain, stretch from our spinal cords to the tips of our toes, paws or fins. According to a ...
Cell & Microbiology
Jun 8, 2010
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Bacterial toxins have always been seen as dangerous molecules—but may also act as negotiators between bacteria and the host immune response to enable long-term infection. Anna Bergonzini, at the Department of Molecular ...
Cell & Microbiology
Feb 16, 2023
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Since Carnegie Institution's Barbara McClintock received her Nobel Prize on her discovery of jumping genes in 1983, we have learned that almost half of our DNA is made up of jumping genes—called transposons. Given their ...
Biotechnology
Nov 1, 2018
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13
When the body machinery that kills off hundreds of millions of cells a day fails, inflammation and sickness are often not far behind.
Cell & Microbiology
Mar 21, 2023
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A pond in Salzburg has been granted nature conservation status due to its unusually diverse population of ciliates. As the results of an Austrian Science Fund FWF research project show, this small water body is home to an ...
Ecology
Aug 26, 2013
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Cancer researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have gained new insights into how cells react to DNA damage. Dr. Michael Stilmann, Dr. Michael Hinz and Professor Claus Scheidereit ...
Cell & Microbiology
Nov 16, 2009
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The first mutation of the wingless gene was found by accident in Drosophila in the 1970s, following the observation of flies that did not possess wings, hence its name. Fifteen years after its discovery, the gene was found ...
Cell & Microbiology
Aug 22, 2022
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33
Plants have developed a robust system that stops their cell cycle in hostile environments such as abnormally hot temperatures. In response, they direct their energy to survival rather than growth. A new study led by scientists ...
Plants & Animals
Apr 5, 2019
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8
Living beings are continuously exposed to harmful agents, both exogenous (ultraviolet radiation, polluting gases, etc.) and endogenous (secondary products of cellular metabolism) that can affect DNA integrity. That's why ...
Cell & Microbiology
Jun 17, 2021
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