Oleoyl-LPE exerts neurite stimulation and neuroprotection

Lysophospholipids are phospholipids that have just one fatty acid chain, and in recent years, the role of lysophospholipids in physiology and pathophysiology has attracted attention. Lysophosphatidylethanolamine (LPE) is ...

Histone degradation after DNA damage enhances repair

DNA damage can occur anywhere in the genome, but most DNA is wrapped around nucleosomes making it inaccessible to the repair machinery. Researchers from the Gasser group now show that DNA damage induces histone depletion, ...

Stem cells aid heart regeneration in salamanders

Imagine filling a hole in your heart by regrowing the tissue. While that possibility is still being explored in people, it is a reality in salamanders. A recent discovery that newt hearts can regenerate may pave the way to ...

New method reveals where DNA is at risk in the cell

Researchers at Karolinska Institutet have developed a new sequencing method that makes it possible to map how DNA is spatially organized in the cell nucleus—revealing which genomic regions are at higher risk of mutation ...

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