Investigators at Burnham Institute for Medical Research (Burnham) have deciphered a large percentage of the total protein complement (proteome) in Schizosaccharomyces pombe (S. pombe) fission yeast.
Cell & Microbiology
Apr 8, 2009
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Two research teams led by Professors Brian Luke and Helle Ulrich at the Institute of Molecular Biology have deciphered how two enzymes, RNase H2 and RNase H1, are coordinated to remove RNA-DNA hybrid structures from chromosomes. ...
Molecular & Computational biology
Nov 27, 2019
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Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases. Their findings, published in the journal ...
Cell & Microbiology
Mar 25, 2020
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Our genomes encounter DNA damaging events continuously. As damage accumulates, our cells react and stop the cell division process, giving repair mechanisms time to act. To achieve this, two master protein kinases called ATR ...
Cell & Microbiology
Dec 19, 2014
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(PhysOrg.com) -- For years, health conscious people have been taking antioxidants to reduce the levels of reactive oxygen in their blood and prevent the DNA damage done by free radicals, which are the result of oxidative ...
Cell & Microbiology
Sep 24, 2009
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DNA damage in general and DNA strand breaks in particular occur every day in all cells of the human body. This is due to internal influences such as free radicals, which are produced during inflammatory processes and cellular ...
Biotechnology
May 1, 2020
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Japanese researchers from Osaka University have uncovered a way in which our cells regulate the repair of broken DNA. Their results, published in the journal Cell Reports show a common molecule regulates multiple repair mechanisms ...
Cell & Microbiology
Jul 12, 2017
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The packaging of a gene has a major impact on its functional state and must be precisely controlled. A novel blend of methods has unveiled the architecture of a large protein complex that modulates DNA packing, and hints ...
Cell & Microbiology
Sep 16, 2013
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Genetic studies in mice have identified a molecular mechanism crucial to maintaining egg cells in a dormant state to ensure female fertility. This work by A*STAR identifies a potential method to prevent infertility when the ...
Cell & Microbiology
Apr 5, 2017
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Since the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered a promising way to generate human, patient-specific stem cells for therapeutic applications. The shortage of ...
Feb 2, 2009
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