St. Jude Children's Research Hospital, founded in 1962, is a leading pediatric treatment and research facility focused on children's catastrophic diseases. It is located in Memphis, Tennessee, and is a nonprofit medical corporation.
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St. Jude Children's Research Hospital scientists are studying the processes that enable cells to respond and adapt to environmental stress, many of which are also associated with neurodegenerative diseases. In complementary ...
Cell & Microbiology
Jun 25, 2021
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Like a boat helping passengers cross a river, transporters move substances across cell membranes. This process is fundamental to the healthy functioning of cells in life forms from bacteria to humans. The function of these ...
Cell & Microbiology
Nov 13, 2019
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July 15, 2019) Life depends on double-stranded DNA unwinding and separating into single strands that can be copied for cell division. St. Jude Children's Research Hospital scientists have determined at atomic resolution the ...
Molecular & Computational biology
Jul 15, 2019
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Scientists at St. Jude Children's Research Hospital have reported a way to improve molecular scale distance measurements using single-molecule fluorescence resonance energy transfer (smFRET). smFRET quantifies the excitation ...
Biotechnology
Jun 14, 2024
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Efficient communication between cells is vital for many biological processes, such as recruiting immune cells to combat disease. The rapid release of at least 80 signaling molecules, including tumor necrosis factor and epidermal ...
Cell & Microbiology
May 22, 2024
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St. Jude Children's Research Hospital scientists have published their work on SJ3149, a compound with broad activity against many cancer types, particularly acute myeloid leukemia (AML). SJ3149 sticks to the cancer-related ...
Biochemistry
Jan 16, 2024
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Scientists at St. Jude Children's Research Hospital are tackling Mycobacterium abscessus (Mab) antibiotic resistance. This naturally antibiotic-resistant pathogen is becoming more prevalent, highlighting the urgent need for ...
Biochemistry
Jan 5, 2024
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St. Jude Children's Research Hospital scientists found that cytonemes (thin, long, hair-like projections on cells) are important during neural development. Cytonemes connect cells communicating across vast distances but are ...
Cell & Microbiology
Jan 2, 2024
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Through an international collaboration, scientists at St. Jude Children's Research Hospital have leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino ...
Molecular & Computational biology
Dec 21, 2023
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The influenza (flu) virus is constantly undergoing a process of evolution and adaptation through acquiring new mutations. Scientists at St. Jude Children's Research Hospital have added a new layer of understanding to explain ...
Evolution
Jul 28, 2023
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