St. Jude Children's Research Hospital, founded in 1962, is a leading pediatric treatment and research facility focused on children's catastrophic diseases. It is located in Memphis, Tennessee, and is a nonprofit medical corporation.
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St. Jude Children's Research Hospital scientists have published their work on SJ3149, a compound with broad activity against many cancer types, particularly acute myeloid leukemia (AML). SJ3149 sticks to the cancer-related ...
Biochemistry
Jan 16, 2024
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Scientists at St. Jude Children's Research Hospital are tackling Mycobacterium abscessus (Mab) antibiotic resistance. This naturally antibiotic-resistant pathogen is becoming more prevalent, highlighting the urgent need for ...
Biochemistry
Jan 5, 2024
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71
St. Jude Children's Research Hospital scientists found that cytonemes (thin, long, hair-like projections on cells) are important during neural development. Cytonemes connect cells communicating across vast distances but are ...
Cell & Microbiology
Jan 2, 2024
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Through an international collaboration, scientists at St. Jude Children's Research Hospital have leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino ...
Molecular & Computational biology
Dec 21, 2023
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The influenza (flu) virus is constantly undergoing a process of evolution and adaptation through acquiring new mutations. Scientists at St. Jude Children's Research Hospital have added a new layer of understanding to explain ...
Evolution
Jul 28, 2023
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St. Jude Children's Research Hospital scientists discovered how the current epizootic H5N1 avian influenza virus (bird flu) gained new genes and greater virulence as it spread west. Researchers showed that the avian virus ...
Evolution
May 30, 2023
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When a cell divides, it retains information about how to grow and instructions about what type of cell to become. Scientists at St. Jude Children's Research Hospital have gained a new understanding of how these processes ...
Cell & Microbiology
May 25, 2023
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118
Like thread tightly wrapped around a spool, DNA is wrapped around histones and packaged into structures called nucleosomes. Scientists at St. Jude Children's Research Hospital are exploring how a type of transcription factor ...
Cell & Microbiology
May 24, 2023
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137
Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity. They captured six structures ...
Cell & Microbiology
May 23, 2023
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83
Scientists at St. Jude Children's Research Hospital revealed that human ribosomes decode messenger RNA (mRNA) 10 times slower than bacterial ribosomes, but do so more accurately. The study, published today in Nature, used ...
Cell & Microbiology
Apr 5, 2023
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