Like a boat helping passengers cross a river, transporters move substances across cell membranes. This process is fundamental to the healthy functioning of cells in life forms from bacteria to humans. The function of these ...
Cell & Microbiology
Nov 13, 2019
0
108
July 15, 2019) Life depends on double-stranded DNA unwinding and separating into single strands that can be copied for cell division. St. Jude Children's Research Hospital scientists have determined at atomic resolution the ...
Molecular & Computational biology
Jul 15, 2019
1
2966
St. Jude Children's Research Hospital scientists have evidence the influenza virus functions like Velcro to help common respiratory bacteria gain a foothold in the airways. The research appears today as an advance online ...
Cell & Microbiology
May 22, 2019
0
22
Researchers led by St. Jude Children's Research Hospital structural biologists have discovered how the cell switches on an executioner mechanism called necroptosis that induces damaged or infected cells to commit suicide ...
Cell & Microbiology
Apr 26, 2019
0
7
St. Jude Children's Research Hospital investigators have developed software to shrink the error rate in next-generation sequencing data by as much as 100-fold, which would likely speed early detection of relapse and other ...
Biotechnology
Mar 14, 2019
0
16
Scientists at St. Jude Children's Research Hospital have mapped key details of how molecular partners regulate assembly of protein-making factories called ribosomes.
Cell & Microbiology
Dec 6, 2018
0
22
Efforts to capitalize on next-generation sequencing to compare gene expression in individual cells for clues about cancer's origins, progression or relapse just got a boost. St. Jude Children's Research Hospital researchers ...
Biotechnology
Jun 20, 2018
0
16
St. Jude Children's Research Hospital scientists have determined how a protein's disordered region serves as a molecular rheostat to help regulate cell survival.
Biochemistry
Mar 6, 2018
0
60
Researchers at St. Jude Children's Research Hospital have discovered that a protein critical to a process called liquid-liquid phase separation within the cell undergoes internal changes in conformation that are key to its ...
Cell & Microbiology
Feb 26, 2018
0
27
Like genealogists filling gaps in a family tree, St. Jude Children's Research Hospital scientists have determined that life-long blood production relies on hundreds more "ancestor" cells than previously reported. The study ...
Cell & Microbiology
Sep 18, 2017
0
18
