St. Jude Children's Research Hospital scientists have identified a novel structure that helps an enzyme solve a challenging biological problem by bobbing like a ship at the surface of the cell membrane. The finding offers ...
Cell & Microbiology
Jul 24, 2017
0
111
St. Jude Children's Research Hospital molecular biologists have identified an enzyme that activates and "supercharges" cellular machinery that controls how cells become specialized cells in the body.
Cell & Microbiology
Jun 6, 2017
0
110
Researchers at St. Jude Children's Research Hospital have discovered the way signals from infectious bacteria gain entry into the cytoplasm of host cells to activate disease-fighting inflammasomes. Inflammasomes are protein ...
Cell & Microbiology
Sep 29, 2016
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13
The H5 avian influenza A virus that devastated North American poultry farms in 2014-15 was initially spread by migratory waterfowl, but evidence suggests such highly pathogenic flu viruses do not persist in wild birds. St. ...
Ecology
Jul 25, 2016
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333
Researchers at St. Jude Children's Research Hospital have uncovered how two enzymes, ULK1 and ULK2, which are best known for their role in the degradation and recycling of proteins, control the trafficking of specific proteins. ...
Cell & Microbiology
May 20, 2016
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6
Researchers at St. Jude Children's Research Hospital have uncovered a new pathway for mitochondrial cell death that involves the protein BCL-2 ovarian killer otherwise known as BOK. The discovery, which is described online ...
Cell & Microbiology
Mar 3, 2016
0
13
Researchers have determined that the protein nucleophosmin (NPM1) serves as glue that holds proteins and RNA together in the nucleolus and showed how NPM1's structure makes it ideal for the job. St. Jude Children's Research ...
Cell & Microbiology
Mar 1, 2016
0
31
St. Jude Children's Research Hospital scientists have identified an enzyme that acts early in pneumococcal infections to promote bacterial survival and invasive disease by removing the bacteria's capsule. The research appears ...
Cell & Microbiology
Feb 29, 2016
0
14
St. Jude Children's Research Hospital scientists have identified a small, drug-like molecule that inhibits the function of a "disordered" protein in research that may advance a novel approach to hearing restoration. The study ...
Cell & Microbiology
Dec 1, 2015
0
7
