St. Jude Children's Research Hospital, founded in 1962, is a leading pediatric treatment and research facility focused on children's catastrophic diseases. It is located in Memphis, Tennessee, and is a nonprofit medical corporation.

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http://www.stjude.org
Wikipedia
http://en.wikipedia.org/wiki/St._Jude_Children%27s_Research_Hospital

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Understanding how autoactivation triggers cell death

Apoptosis is a process that causes cell death. It can go awry in cancer cells, sustaining the disease. Scientists at St. Jude Children's Research Hospital have captured the structure of BAK, a protein that triggers apoptosis. ...

Evidence for how a key transcription factor manages access to DNA

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC. Scientists at St. Jude Children's Research Hospital have found direct evidence that CTCF governs ...

Research illuminates earliest part of phase separation

Scientists at St. Jude Children's Research Hospital are studying liquid-liquid phase separation (LLPS), a biophysical process through which proteins and nucleic acids in a cell are compartmentalized without a membrane. The ...

Researchers capture six new structures of the ribosome in action

St. Jude Children's Research Hospital scientists have used single-molecule fluorescence resonance energy transfer (smFRET) and cryogenic electron microscopy (cryo-EM) to capture six new structures of the ribosome and its ...

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