Millions exposed to potentially dangerous metals, new technology could help lower the risk

August 10, 2018, Purdue University
Linda Nie, an associate professor in Purdue University’s School of Health Sciences, helped create new technology to try to reduce the number of people impacted by health problems associated with the accumulation of metals in the body. Credit: Purdue University

A unique system developed by Purdue University researchers may help reduce the number of people impacted by health problems associated with the accumulation of metals in the body.

The technology detects manganese, a known neurotoxicant in high concentrations, which more than 1 million people in the United States are exposed to each year through their work in areas such as welding and construction, or during daily activities, such as eating food and drinking water.

Overexposure can lead to impaired cognitive and motor functions. At higher levels, it can result in a permanent neurological disorder with symptoms similar to Parkinson's disease.

"The accumulation of manganese or other metals in the body can have serious impacts on the brain, kidney, liver and other organs," said Linda Nie, an associate professor in Purdue's School of Health Sciences, who led the research team. "We want to use our technology to assess the exposure levels and to prevent progressive and permanent damage. This technology we have developed opens up a new door for metal exposure assessment and quantification and the research on metals and associated health effects on humans."

The Purdue metal detection technology is a neutron generator based activation analysis system that quantifies metals, such as manganese, in the bone in vivo. The neutrons interact with the metals in the bone and emit elemental specific gamma rays, which are collected and provide information about the exposure.

"Our novel, non-invasive technology is a giant leap for in-vivo quantification that may help improve the lives of thousands of people by identifying overexposure to or insufficient intake of essential metals," Nie said. "Currently it is the only technology which can noninvasively assess long-term cumulative exposure to manganese and some other metals for an individual."

This technology uses a compact neutron generator, which reduces space and complications that come from larger devices, and makes it mobile and transportable. Researchers also are looking to use the same technology to quantify other metals such as aluminum, cadmium, sodium in bones and other targeted or storage tissues.

Nie said that the system could also be used to provide data to show the need for improved worker policies and water supply practices to limit exposure to metals.

Explore further: Metals in local groceries may impact kids health

Related Stories

Metal exposure – a factor in bat population decline

June 9, 2016

Scientists at the University of York have led the first full-scale national assessment of metal contamination in bats, showing that many bats in the UK contain levels of metals high enough to cause toxic effects.

Removing heavy metals from water with MOFs

March 14, 2018

An estimated 1 billion people do not have access to clean drinking water, a problem expected to worsen with climate change, according to the World Health Organization. In addition, higher energy needs and increased use of ...

Troubling levels of toxic metals found in lipstick

May 2, 2013

A new analysis of the contents of lipstick and lip gloss may cause you to pause before puckering. Researchers at the University of California, Berkeley's School of Public Health tested 32 different lipsticks and lip glosses ...

Recommended for you

Lipid droplets play crucial roles beyond fat storage

August 14, 2018

Lipid droplets: they were long thought of merely as the formless blobs of fat out of which spare tires and muffin tops were made. But these days, they're "a really hot area of research," says Michael Welte, professor and ...

Bacteria-fighting polymers created with light

August 14, 2018

Hundreds of polymers that could kill drug-resistant superbugs in novel ways can be produced and tested with light, using a method developed at the University of Warwick. The new methodology may identify antimicrobials for ...

Transforming gas into fuels with better alloys

August 14, 2018

Technological advances in oil and gas well stimulation over the past decade now allow for the production of natural gas from shale gas trapped in rock formations underground. With the sudden increase in the availability of ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.