June 27, 2016

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Micro-camera can be injected with a syringe

Regular arrangement of doublet lenses directly fabricated on a CMOS image sensor. Credit: Timo Gissibl
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Regular arrangement of doublet lenses directly fabricated on a CMOS image sensor. Credit: Timo Gissibl

German engineers have created a camera no bigger than a grain of salt that could change the future of health imaging—and clandestine surveillance.

Using 3-D printing, researchers from the University of Stuttgart built a three-lens , and fit it onto the end of an optical fibre the width of two hairs.

Such technology could be used as minimally-intrusive endoscopes for exploring inside the human body, the engineers reported in the journal Nature Photonics.

It could also be deployed in virtually invisible security monitors, or mini-robots with "autonomous vision".

3-D printing—also known as additive manufacturing—makes three-dimensional objects by depositing layer after layer of materials such as plastic, metal or ceramic.

Due to manufacturing limitations, lenses cannot currently be made small enough for key uses in the medical field, said the team, which believe its 3-D printing method may represent "a paradigm shift".

It took only a few hours to design, manufacture and test the tiny eye, which yielded "high optical performances and tremendous compactness," the researchers reported.

The compound lens is just 100 micrometres (0.1 millimetres or 0.004 inches) wide, and 120 micrometres with its casing.

Image of a multi-lens system with a diameter of 600 µm next to a doublet lenses with a diameter of 120 µm. Credit: Timo Gissibl
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Image of a multi-lens system with a diameter of 600 µm next to a doublet lenses with a diameter of 120 µm. Credit: Timo Gissibl

It can focus on images from a distance of 3.0 mm, and relay them over the length of a 1.7-metre (5.6-foot) optical fibre to which it is attached.

The "imaging system" fits comfortably inside a standard syringe needle, said the team, allowing for delivery into a human organ, or even the brain.

"Endoscopic applications will allow for non-invasive and non-destructive examination of small objects in the medical as well as the industrial sector," they wrote.

The compound lense can also be printed onto image sensor other than optical fibres, such as those used in digital cameras.

Image of a multi-lens system with a diameter of 600 µm surrounded by four doublet lenses with a diameter of 120 µm. Credit: Timo Gissibl
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Image of a multi-lens system with a diameter of 600 µm surrounded by four doublet lenses with a diameter of 120 µm. Credit: Timo Gissibl
Colored SEM-image of a miniature triplet lens directly fabricated on an optical fiber. Credit: Timo Gissibl
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Colored SEM-image of a miniature triplet lens directly fabricated on an optical fiber. Credit: Timo Gissibl

More information: Two-photon direct laser writing of ultracompact multi-lens objectives, Nature Photonics, nature.com/articles/doi:10.1038/nphoton.2016.121

Journal information: Nature Photonics

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